Ghostbusters (1984)

Fired from their university research jobs, Drs. Venkman, Stantz, and Spengler promptly set up shop as parapsychologists specializing in psychic phenomena and soon they're ridding Manhattan of bizarre apparitions. But the talents of these spirit exterminators--Ghostbusters--are severely tested when beautiful Dana Barrett and her nerdy neighbor become possessed by demons living in their building.