Cursed (2005)

Ellie Myers, an assistant on ‘The Craig Kilborn Show’, is driving home through the Hollywood Hills with her teenage brother Jimmy when an animal runs out, hitting the car and causing them to crash into another vehicle. They go to the other driver’s aid, only to see her snatched away and torn in half by the animal. Later Jimmy is certain that the animal was a werewolf. Both he and Ellie were bitten by it and discover that they now have pentacles imprinted on their palms. As they go about their lives at work and school, both of them find more aggressive urges and animalistic behaviour coming through. But at the same time, the original wolf creature is still out there, claiming victims.