The unluckiest man in Vegas (William H. Macy) - a guy whose bad luck is contagious - is used by the last of the old time mob run casinos to kill high rollers' action. That is, until he falls in love with a cocktail waitress (Maria Bello) and gets "lady luck," which throws the situation into reverse. Things turn nasty when the casino director (Alec Baldwin) tries to break up the romance.
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