Garden State (2004)

When Andrew Largeman (Zach Braff) returns to his hometown for his mother’s funeral, he reconnects with old friends and - since he’s gone off his depression medication - himself. A chance meeting with Sam (Natalie Portman), who also suffering from various maladies, opens his world to the possibility of rekindling emotional attachments, confronting his psychologist father, and perhaps beginning a new life.